Implementation of schematic physiologicaly based pharmacokinetics (PBPK) model, with simplified GUT and liver and kidney elimination. [1]
References:
[1] Jones, H. M., & Rowland-Yeo, K. (2013). Basic concepts in physiologically based pharmacokinetic modeling in drug discovery and development. CPT: Pharmacometrics and Systems Pharmacology, 2(8). https://doi.org/10.1038/psp.2013.41