.Pharmacolibrary.DevModels.Systems.PKOneCompartmentEquations

One compartment model implemented as equation. For testing and benchmark purposes.

parameters and equations

F - bioavailability (0-1)

Vd - volume of distribution (m3), if in l/kg recalculate it to m3 with respect to patient weight

numDoses - number of doses (1-10)

doseFirst - first dose (kg) if in mg recalculate to kg

doseSubsequent - subsequent doses (kg)  if in mg recalculate to kg

t0 - time of first dose

Cl -clearance (m3/s), if in L/h, recalculate it

C = F * dose/Vd * e^(-Cl/Vd*(time-t0))