.Pharmacolibrary.Drugs.ATC.A.A01AA51 .Pharmacolibrary.Drugs.ATC.A.A01AA51| name: | SodiumFluorideCombinations |
| ATC code: | A01AA51 | route: | oral |
| n-compartments | 1 |
Sodium fluoride, in combination with other agents, is typically used topically or systemically for the prevention of dental caries through the promotion of remineralization of tooth enamel. Its systemic use is less common nowadays, and its main indication is dental hygiene and prevention of cavities. It is generally regarded as safe when used as indicated, but systemic application is not routinely recommended for general populations in most countries today.
Estimated typical pharmacokinetics in healthy adults, based on available data for sodium fluoride; no direct studies found for combinations under ATC code A01AA51.
Lin, YS, et al., & Milgrom, P (2018). Pharmacokinetics of Iodine and Fluoride following Application of an Anticaries Varnish in Adults. JDR clinical and translational research 3(3) 238–245. DOI:10.1177/2380084418771930 PUBMED:https://pubmed.ncbi.nlm.nih.gov/30938600
Ivanoff, CS, et al., & Garcia-Godoy, F (2013). Enhanced penetration of fluoride particles into bovine enamel by combining dielectrophoresis with AC electroosmosis. Electrophoresis 34(20-21) 2945–2955. DOI:10.1002/elps.201300206 PUBMED:https://pubmed.ncbi.nlm.nih.gov/23897721