name: | Chlortetracycline |
ATC code: | A01AB21 | route: | oral |
n-compartments | 1 |
Chlortetracycline is a broad-spectrum tetracycline antibiotic formerly used to treat various bacterial infections in humans and animals. It is predominantly used in veterinary medicine today and is rarely used in humans due to the availability of newer antibiotics and concerns regarding resistance and toxicity.
Estimated pharmacokinetic parameters for an average adult, as no directly reported human PK data were found in the literature for chlortetracycline.
Zhang, Y, et al., & Yu, M (2022). Florfenicol/Chlortetracycline Effect on Pharmacodynamic Indices for Mutant Selection of . Microbial drug resistance (Larchmont, N.Y.) 28(7) 832–840. DOI:10.1089/mdr.2022.0008 PUBMED:https://pubmed.ncbi.nlm.nih.gov/35723674
Cazer, CL, et al., & Gröhn, YT (2018). Expanding behavior pattern sensitivity analysis with model selection and survival analysis. BMC veterinary research 14(1) 355–None. DOI:10.1186/s12917-018-1674-y PUBMED:https://pubmed.ncbi.nlm.nih.gov/30453986
Cazer, CL, et al., & Gröhn, YT (2017). Monte Carlo Simulations Suggest Current Chlortetracycline Drug-Residue Based Withdrawal Periods Would Not Control Antimicrobial Resistance Dissemination from Feedlot to Slaughterhouse. Frontiers in microbiology 8 1753–None. DOI:10.3389/fmicb.2017.01753 PUBMED:https://pubmed.ncbi.nlm.nih.gov/29033901