.Pharmacolibrary.Drugs.ATC.A.A01AC03 .Pharmacolibrary.Drugs.ATC.A.A01AC03| name: | Hydrocortisone |
| ATC code: | A01AC03 | route: | oral |
| n-compartments | 1 |
Hydrocortisone is a synthetic corticosteroid used primarily for its anti-inflammatory and immunosuppressive effects. It is employed in the treatment of conditions such as adrenal insufficiency, severe allergies, skin diseases, and as a topical agent in oral preparations for inflammation in the mouth. It is an approved and widely used medication.
Pharmacokinetic parameters reported in healthy adult volunteers following oral administration.
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Werumeus Buning, J, et al., & van Beek, AP (2017). Pharmacokinetics of oral hydrocortisone - Results and implications from a randomized controlled trial. Metabolism: clinical and experimental 71 7–16. DOI:10.1016/j.metabol.2017.02.005 PUBMED:https://pubmed.ncbi.nlm.nih.gov/28521880
Polito, A, et al., & Alvarez, JC (2016). Pharmacokinetics of oral fludrocortisone in septic shock. British journal of clinical pharmacology 82(6) 1509–1516. DOI:10.1111/bcp.13065 PUBMED:https://pubmed.ncbi.nlm.nih.gov/27416887