.Pharmacolibrary.Drugs.ATC.A.A02AB10 .Pharmacolibrary.Drugs.ATC.A.A02AB10| name: | OmeprazoleAmoxicillinAndClarithromycinCombination | |
| ATC code: | A02AB10 | route: | oral |
| compartments: | 1 | |
| dosage: | 20 | mg |
| volume of distribution: | 0.3 | L |
| clearance: | 500 | mL/min |
| other parameters in model implementation | ||
This is a fixed-dose combination therapy used primarily for the eradication of Helicobacter pylori infection to reduce the risk of duodenal ulcer recurrence. The combination includes a proton pump inhibitor (omeprazole) and two antibiotics (amoxicillin and clarithromycin). The combination is approved and commonly used as part of triple therapy for H. pylori infection.
Estimated pharmacokinetic parameters for adult healthy volunteers, based on published PK profiles of each component; no clinical publication on the fixed-dose A02AB10 combo PK.