name: | Propantheline |
ATC code: | A03AB05 | route: | oral |
n-compartments | 1 |
Propantheline is an antimuscarinic/anticholinergic agent used to treat peptic ulcers and various gastrointestinal disorders, as well as to reduce salivation and excessive sweating. It is not widely used today due to the availability of safer alternatives and its adverse side-effect profile.
Pharmacokinetic parameters reported for healthy adult subjects after oral administration.
Forrest, JA, et al., & Prescott, LF (1982). Clinical pharmacokinetics of paracetamol. Clinical pharmacokinetics 7(2) 93–107. DOI:10.2165/00003088-198207020-00001 PUBMED:https://pubmed.ncbi.nlm.nih.gov/7039926
Guay, DR (2003). Clinical pharmacokinetics of drugs used to treat urge incontinence. Clinical pharmacokinetics 42(14) 1243–1285. DOI:10.2165/00003088-200342140-00004 PUBMED:https://pubmed.ncbi.nlm.nih.gov/14606931
Yarker, YE, et al., & Fitton, A (1995). Oxybutynin. A review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic use in detrusor instability. Drugs & aging 6(3) 243–262. DOI:10.2165/00002512-199506030-00007 PUBMED:https://pubmed.ncbi.nlm.nih.gov/7620236