.Pharmacolibrary.Drugs.ATC.A.A03AB05

Information

name:Propantheline
ATC code:A03AB05
route:oral
compartments:1
dosage:30mg
volume of distribution:1.67L
clearance:9.5mL/min/kg
other parameters in model implementation

Propantheline is an antimuscarinic/anticholinergic agent used to treat peptic ulcers and various gastrointestinal disorders, as well as to reduce salivation and excessive sweating. It is not widely used today due to the availability of safer alternatives and its adverse side-effect profile.

Pharmacokinetics

Pharmacokinetic parameters reported for healthy adult subjects after oral administration.

References

  1. Forrest, JA, et al., & Prescott, LF (1982). Clinical pharmacokinetics of paracetamol. Clinical pharmacokinetics 7(2) 93–107. DOI:10.2165/00003088-198207020-00001 PUBMED:https://pubmed.ncbi.nlm.nih.gov/7039926

  2. Guay, DR (2003). Clinical pharmacokinetics of drugs used to treat urge incontinence. Clinical pharmacokinetics 42(14) 1243–1285. DOI:10.2165/00003088-200342140-00004 PUBMED:https://pubmed.ncbi.nlm.nih.gov/14606931

  3. Yarker, YE, et al., & Fitton, A (1995). Oxybutynin. A review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic use in detrusor instability. Drugs & aging 6(3) 243–262. DOI:10.2165/00002512-199506030-00007 PUBMED:https://pubmed.ncbi.nlm.nih.gov/7620236

Revisions


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