.Pharmacolibrary.Drugs.ATC.A.A06AX03 .Pharmacolibrary.Drugs.ATC.A.A06AX03| name: | Lubiprostone | |
| ATC code: | A06AX03 | route: | oral |
| compartments: | 1 | |
| dosage: | 24 | mg |
| volume of distribution: | 35 | L |
| clearance: | 250 | L/h |
| other parameters in model implementation | ||
Lubiprostone is a chloride channel activator used for the treatment of chronic idiopathic constipation, opioid-induced constipation, and irritable bowel syndrome with constipation (IBS-C) in adults. It is approved by regulatory agencies such as the FDA and is currently in clinical use.
Pharmacokinetics of lubiprostone after oral administration in healthy adult volunteers as referenced in the published literature.