.Pharmacolibrary.Drugs.ATC.A.A07AA12

Information

name:Fidaxomicin
ATC code:A07AA12
route:oral
n-compartments1

Fidaxomicin is a narrow-spectrum macrocyclic antibiotic used primarily for the treatment of Clostridioides difficile-associated diarrhea. It is approved for use in adults and children and exhibits minimal systemic absorption, acting mainly in the gastrointestinal tract.

Pharmacokinetics

Pharmacokinetics reported in healthy adult volunteers following oral administration.

References

  1. Daniels, T, & So, TY (2011). Fidaxomicin for the Treatment of Clostridium Difficile Infection in the Pediatric Population - Not Quite So Soon Yet. Gastroenterology research 4(3) 93–96. DOI:10.4021/gr318e PUBMED:https://pubmed.ncbi.nlm.nih.gov/27942322

  2. Skinner, AM, et al., & Kociolek, LK (2020). Fidaxomicin for the treatment of . Future microbiology 15(11) 967–979. DOI:10.2217/fmb-2020-0104 PUBMED:https://pubmed.ncbi.nlm.nih.gov/32715754

  3. Vande Griend, JP, et al., & Linnebur, SA (2012). A year in review: new drugs for older adults in 2011. The American journal of geriatric pharmacotherapy 10(4) 258–263. DOI:10.1016/j.amjopharm.2012.05.003 PUBMED:https://pubmed.ncbi.nlm.nih.gov/22682643

Revisions

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