.Pharmacolibrary.Drugs.ATC.A.A07EA01 .Pharmacolibrary.Drugs.ATC.A.A07EA01| name: | Prednisolone |
| ATC code: | A07EA01 | route: | oral |
| n-compartments | 2 |
Prednisolone is a synthetic glucocorticoid used as an anti-inflammatory and immunosuppressive agent in the treatment of various conditions, including allergic disorders, autoimmune diseases, and inflammatory conditions. It is approved for clinical use and remains a widely prescribed corticosteroid.
Pharmacokinetic parameters reported in healthy adult volunteers after single oral administration.
de Truchis, C, et al., & Boyer, O (2023). Prednisolone pharmacokinetics after oral prednisone administration in paediatric patients with kidney transplant. British journal of clinical pharmacology 89(5) 1532–1540. DOI:10.1111/bcp.15610 PUBMED:https://pubmed.ncbi.nlm.nih.gov/36510685
Petersen, KB, et al., & Schmiegelow, K (2003). Population pharmacokinetics of prednisolone in children with acute lymphoblastic leukemia. Cancer chemotherapy and pharmacology 51(6) 465–473. DOI:10.1007/s00280-003-0602-3 PUBMED:https://pubmed.ncbi.nlm.nih.gov/12698270
Yoshida, K, et al., & Chanu, P (2021). Population Pharmacokinetics of Ipatasertib and Its Metabolite in Cancer Patients. Journal of clinical pharmacology 61(12) 1579–1591. DOI:10.1002/jcph.1942 PUBMED:https://pubmed.ncbi.nlm.nih.gov/34273118