.Pharmacolibrary.Drugs.ATC.A.A10AD01 .Pharmacolibrary.Drugs.ATC.A.A10AD01| name: | InsulinHuman | |
| ATC code: | A10AD01 | route: | subcutaneous |
| compartments: | 2 | |
| dosage: | 0.1 | mg |
| volume of distribution: | 0.095 | L |
| clearance: | 1.2 | mL/min/kg |
| other parameters in model implementation | ||
Human insulin is a polypeptide hormone used to regulate blood glucose levels in the treatment of diabetes mellitus (Type 1 and Type 2). It mimics the action of endogenous insulin and is approved for clinical use worldwide in both adult and pediatric populations to control hyperglycemia.
Pharmacokinetic parameters based on published study in healthy male subjects following subcutaneous administration of regular human insulin.
Setji, TL, et al., & Feinglos, MN (2016). Technosphere insulin: inhaled prandial insulin. Expert opinion on biological therapy 16(1) 111–117. DOI:10.1517/14712598.2016.1121230 PUBMED:https://pubmed.ncbi.nlm.nih.gov/26567896