.Pharmacolibrary.Drugs.ATC.A.A10AE30

Information

name:InsulinDegludecAndLiraglutide
ATC code:A10AE30
route:subcutaneous
compartments:2
dosage:16mg
volume of distribution:10.0L
clearance:0.03L/h
other parameters in model implementation

Combination of insulin degludec, an ultra-long-acting basal insulin analogue, and liraglutide, a GLP-1 receptor agonist. Used in the management of type 2 diabetes mellitus to improve glycemic control. Approved by regulatory agencies in many countries under the brand name Xultophy.

Pharmacokinetics

Pharmacokinetic parameters estimated for healthy adults based on published single-agent studies and product information. No single-population PK study directly available for the fixed combination product.

References

    Revisions


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