.Pharmacolibrary.Drugs.ATC.A.A10BA01

Information

name:Phenformin
ATC code:A10BA01
route:oral
n-compartments1

Phenformin is a biguanide class oral antihyperglycemic agent that was previously used for the management of type 2 diabetes mellitus. Due to a high risk of lactic acidosis, phenformin has been withdrawn from the market in most countries and is no longer approved for clinical use.

Pharmacokinetics

Pharmacokinetic parameters reported for healthy adults following oral administration.

References

  1. Scheen, AJ (1996). Clinical pharmacokinetics of metformin. Clinical pharmacokinetics 30(5) 359–371. DOI:10.2165/00003088-199630050-00003 PUBMED:https://pubmed.ncbi.nlm.nih.gov/8743335

  2. Scheen, AJ, & Lefèbvre, PJ (1995). Antihyperglycaemic agents. Drug interactions of clinical importance. Drug safety 12(1) 32–45. DOI:10.2165/00002018-199512010-00003 PUBMED:https://pubmed.ncbi.nlm.nih.gov/7741982

  3. Marchetti, P, et al., & Navalesi, R (1991). Pharmacokinetic optimisation of oral hypoglycaemic therapy. Clinical pharmacokinetics 21(4) 308–317. DOI:10.2165/00003088-199121040-00006 PUBMED:https://pubmed.ncbi.nlm.nih.gov/1760902

Revisions

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