.Pharmacolibrary.Drugs.ATC.A.A10BA03

Information

name:Buformin
ATC code:A10BA03
route:oral
n-compartments1

Buformin is a biguanide class oral antihyperglycemic agent that was used to treat type 2 diabetes mellitus. It works by decreasing hepatic glucose production and improving insulin sensitivity. Buformin is not widely used today due to its risk of lactic acidosis and has been withdrawn from the market in many countries.

Pharmacokinetics

Pharmacokinetic parameters in healthy adult volunteers after oral administration.

References

  1. Scheen, AJ, & Lefèbvre, PJ (1995). Antihyperglycaemic agents. Drug interactions of clinical importance. Drug safety 12(1) 32–45. DOI:10.2165/00002018-199512010-00003 PUBMED:https://pubmed.ncbi.nlm.nih.gov/7741982

  2. Marchetti, P, et al., & Navalesi, R (1991). Pharmacokinetic optimisation of oral hypoglycaemic therapy. Clinical pharmacokinetics 21(4) 308–317. DOI:10.2165/00003088-199121040-00006 PUBMED:https://pubmed.ncbi.nlm.nih.gov/1760902

Revisions

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