.Pharmacolibrary.Drugs.ATC.A.A10BD10

Information

name:MetforminAndSaxagliptin
ATC code:A10BD10
route:oral
compartments:1
dosage:1000mg
volume of distribution:63L
clearance:10.0L/h
other parameters in model implementation

Combination of metformin, a biguanide antihyperglycemic agent, and saxagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor. Used for the treatment of type 2 diabetes mellitus to improve glycemic control, as an adjunct to diet and exercise. Approved for use in multiple regions.

Pharmacokinetics

Estimated pharmacokinetic parameters for healthy adults based on published data for individual components; no direct published pharmacokinetics of combination found.

References

    Revisions


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