.Pharmacolibrary.Drugs.ATC.A.A10BD28 .Pharmacolibrary.Drugs.ATC.A.A10BD28| name: | MetforminAndTeneligliptin |
| ATC code: | A10BD28 | route: | oral |
| n-compartments | 1 |
Metformin and teneligliptin is a fixed dose combination of two antidiabetic agents: metformin, a biguanide that reduces hepatic glucose production and increases insulin sensitivity, and teneligliptin, a DPP-4 inhibitor that increases incretin levels and glucose-dependent insulin secretion. This combination is approved and widely used for the treatment of type 2 diabetes mellitus in adults to improve glycemic control.
Estimated pharmacokinetic parameters for typical adult population receiving the fixed-dose combination orally. No primary published population pharmacokinetic (PopPK) models for the combination product found; parameters are based on known monotherapy PK data and fixed dose combination prescribing information.