name: | GemigliptinAndRosuvastatin | |
ATC code: | A10BH52 | route: | oral |
compartments: | 1 | |
dosage: | 50 | mg |
volume of distribution: | 100 | L |
clearance: | 14 | L/h |
other parameters in model implementation |
Gemigliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor used for glycemic control in type 2 diabetes mellitus, while rosuvastatin is a statin medication used to lower cholesterol levels and prevent cardiovascular disease. The fixed-dose combination (ATC: A10BH52) is approved for co-management of hyperglycemia and hyperlipidemia in adults with type 2 diabetes and dyslipidemia.
No published population pharmacokinetic model found for the combination product. Pharmacokinetics are estimated from data for each drug in healthy adult subjects under fasting, oral administration conditions.