.Pharmacolibrary.Drugs.ATC.A.A11CA02 .Pharmacolibrary.Drugs.ATC.A.A11CA02| name: | Betacarotene | |
| ATC code: | A11CA02 | route: | oral |
| compartments: | 1 | |
| dosage: | 15 | mg |
| volume of distribution: | 2 | L |
| clearance: | 0.4 | L/h/kg |
| other parameters in model implementation | ||
Beta-carotene is a precursor of vitamin A (provitamin A carotenoid) and functions as an antioxidant. It is used as a dietary supplement for vitamin A deficiency and as a food coloring. Despite its historical use in preventing chronic diseases, supplemental beta-carotene is no longer recommended for general populations due to inconclusive effectiveness and possible harm in smokers.
Estimated parameters for healthy adults; published clinical studies have not consistently reported detailed compartmental pharmacokinetic parameters in humans.
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Newcomb, SA, et al., & Davis, TP (1990). Endogenous levels of beta-carotene in human buccal mucosa cells by reversed-phase high-performance liquid chromatography. Journal of chromatography 526(1) 47–58. DOI:10.1016/s0378-4347(00)82482-2 PUBMED:https://pubmed.ncbi.nlm.nih.gov/2341545