.Pharmacolibrary.Drugs.ATC.A.A16AX09 .Pharmacolibrary.Drugs.ATC.A.A16AX09| name: | GlycerolPhenylbutyrate |
| ATC code: | A16AX09 | route: | oral |
| n-compartments | 1 |
Glycerol phenylbutyrate is a prodrug for phenylbutyric acid, approved for chronic management of urea cycle disorders. It is used to help control hyperammonemia by delivering phenylacetate, which serves as a nitrogen scavenger. The drug is currently approved and marketed for use in both pediatric and adult populations with urea cycle disorders.
Pharmacokinetic parameters from published clinical studies in healthy adults and patients with urea cycle disorders. Most data are for oral administration of therapeutic doses.