.Pharmacolibrary.Drugs.ATC.B.B01AB04

Information

name:Dalteparin
ATC code:B01AB04
route:subcutaneous
compartments:1
dosage:5000mg
volume of distribution:0.07L
clearance:1.68mL/min/kg
other parameters in model implementation

Dalteparin is a low molecular weight heparin (LMWH) used as an anticoagulant for the prevention and treatment of deep vein thrombosis, pulmonary embolism, and for prophylaxis in patients undergoing surgery or at increased risk of thromboembolic events. It is approved and widely used today for these indications.

Pharmacokinetics

Pharmacokinetic parameters in healthy adult volunteers (both male and female) after single subcutaneous injection.

References

  1. Damle, B, et al., & Sweeney, K (2021). Population Pharmacokinetic Analysis of Dalteparin in Pediatric Patients With Venous Thromboembolism. Journal of clinical pharmacology 61(2) 172–180. DOI:10.1002/jcph.1716 PUBMED:https://pubmed.ncbi.nlm.nih.gov/32827160

  2. Howard, PA (1997). Dalteparin: a low-molecular-weight heparin. The Annals of pharmacotherapy 31(2) 192–203. DOI:10.1177/106002809703100212 PUBMED:https://pubmed.ncbi.nlm.nih.gov/9034422

  3. Yu, L, et al., & Guo, R (2018). Pharmacodynamic properties and bioequivalence of dalteparin sodium subcutaneous injection in healthy Chinese male subjects. Xenobiotica; the fate of foreign compounds in biological systems 48(4) 376–381. DOI:10.1080/00498254.2017.1316021 PUBMED:https://pubmed.ncbi.nlm.nih.gov/28375032

Revisions


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