name: | Desirudin | |
ATC code: | B01AE01 | route: | subcutaneous |
compartments: | 1 | |
dosage: | 15 | mg |
volume of distribution: | 0.25 | L |
clearance: | 1.5 | L/h |
other parameters in model implementation |
Desirudin is a recombinant hirudin, a direct thrombin inhibitor used for prophylaxis of deep vein thrombosis (DVT) in patients undergoing elective hip replacement surgery. It acts by inhibiting free and clot-bound thrombin. Desirudin is approved for medical use but is not widely available in all countries.
Pharmacokinetic parameters reported in healthy adults after subcutaneous administration.