.Pharmacolibrary.Drugs.ATC.B.B02BD13 .Pharmacolibrary.Drugs.ATC.B.B02BD13| name: | CoagulationFactorX | |
| ATC code: | B02BD13 | route: | intravenous |
| compartments: | 1 | |
| dosage: | 25 | mg |
| volume of distribution: | 0.049 | L |
| clearance: | 0.7 | mL/h/kg |
| other parameters in model implementation | ||
Coagulation factor X is a vitamin K-dependent plasma glycoprotein produced in the liver that plays a key role in the coagulation cascade. Recombinant or plasma-derived factor X concentrates are used for the treatment and prevention of bleeding episodes in patients with hereditary factor X deficiency. Coagulation factor X replacement therapies are approved for use in individuals with this rare coagulation disorder.
Pharmacokinetic parameters are reported in adults with hereditary factor X deficiency after intravenous administration of plasma-derived factor X.