.Pharmacolibrary.Drugs.ATC.B.B02BX08 .Pharmacolibrary.Drugs.ATC.B.B02BX08| name: | Avatrombopag | |
| ATC code: | B02BX08 | route: | oral |
| compartments: | 2 | |
| dosage: | 20 | mg |
| volume of distribution: | 180 | L |
| clearance: | 6.9 | L/h |
| other parameters in model implementation | ||
Avatrombopag is an orally administered small molecule thrombopoietin receptor agonist that is used to treat thrombocytopenia, particularly in patients with chronic liver disease scheduled to undergo a medical or dental procedure and in patients with chronic immune thrombocytopenia (ITP). It is an approved medication.
Pharmacokinetic parameters reported in healthy adult subjects following oral administration.
Grace, RF, et al., & Jamieson, BD (2025). Avatrombopag for the treatment of children and adolescents with immune thrombocytopenia (AVA-PED-301): a multicentre, randomised, double-blind, placebo-controlled, phase 3b study. The Lancet. Haematology None –. DOI:10.1016/S2352-3026(25)00107-3 PUBMED:https://pubmed.ncbi.nlm.nih.gov/40418942