.Pharmacolibrary.Drugs.ATC.B.B03BA01

Information

name:Cyanocobalamin
ATC code:B03BA01
route:intramuscular
compartments:2
dosage:1000mg
volume of distribution:1.02L
clearance:3.13mL/min
other parameters in model implementation

Cyanocobalamin is a synthetic form of vitamin B12 used to treat and prevent vitamin B12 deficiency. It is essential for DNA synthesis, red blood cell maturation, and neurological function. It is approved and widely used today.

Pharmacokinetics

Pharmacokinetic parameters are reported for adult healthy volunteers after intramuscular and oral administration.

References

  1. Sezer, RG, et al., & Özdemir, GN (2018). Comparison of the efficacy of parenteral and oral treatment for nutritional vitamin B12 deficiency in children. Hematology (Amsterdam, Netherlands) 23(9) 653–657. DOI:10.1080/10245332.2018.1456023 PUBMED:https://pubmed.ncbi.nlm.nih.gov/29577819

  2. Mezzano, D, et al., & Leighton, F (2000). Cardiovascular risk factors in vegetarians. Normalization of hyperhomocysteinemia with vitamin B(12) and reduction of platelet aggregation with n-3 fatty acids. Thrombosis research 100(3) 153–160. DOI:10.1016/s0049-3848(00)00313-3 PUBMED:https://pubmed.ncbi.nlm.nih.gov/11108902

Revisions


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