.Pharmacolibrary.Drugs.ATC.B.B03BB01

Information

Folic acid (vitamin B9) is a water-soluble B vitamin used for the prevention and treatment of folate deficiency, including in conditions such as anemia, during pregnancy to prevent neural tube defects, and in certain methotrexate toxicities. It is widely available as an oral supplement and approved for use today.

Pharmacokinetics

Pharmacokinetic parameters reported in healthy adult volunteers following a single oral dose of folic acid.

References

1. Lee, SK (2023). Issues of Women with Epilepsy and Suitable Antiseizure Drugs. Journal of epilepsy research 13(2) 23–35. DOI:10.14581/jer.23005 PUBMED:https://pubmed.ncbi.nlm.nih.gov/38223363

2. Genton, P, et al., & Trinka, E (2006). Valproic acid in epilepsy : pregnancy-related issues. Drug safety 29(1) 1–21. DOI:10.2165/00002018-200629010-00001 PUBMED:https://pubmed.ncbi.nlm.nih.gov/16454531

3. Bayes, J, et al., & Schloss, J (2019). The Bioavailability of Various Oral Forms of Folate Supplementation in Healthy Populations and Animal Models: A Systematic Review. Journal of alternative and complementary medicine (New York, N.Y.) 25(2) 169–180. DOI:10.1089/acm.2018.0086 PUBMED:https://pubmed.ncbi.nlm.nih.gov/30010385

Revisions

• 06/2025 initial generated model