.Pharmacolibrary.Drugs.ATC.B.B03XA01_1

Information

name:Erythropoietin_1
ATC code:B03XA01_1
route:subcutaneous
n-compartments2

Erythropoietin is a glycoprotein hormone used to stimulate erythropoiesis (red blood cell production) in patients with anemia, particularly anemia associated with chronic kidney disease, chemotherapy, or certain treatments for HIV. Recombinant human erythropoietin (epoetin alfa and similar agents) is approved and widely used in clinical practice.

Pharmacokinetics

Pharmacokinetic parameters of recombinant human erythropoietin (epoetin alfa) administered subcutaneously to adult healthy volunteers.

References

  1. D'Cunha, R, et al., & An, G (2019). Target-mediated disposition population pharmacokinetics model of erythropoietin in premature neonates following multiple intravenous and subcutaneous dosing regimens. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 138 105013–None. DOI:10.1016/j.ejps.2019.105013 PUBMED:https://pubmed.ncbi.nlm.nih.gov/31340188

  2. An, G, et al., & Veng-Pedersen, P (2017). Population Pharmacokinetics of Darbepoetin in Infants Following Single Intravenous and Subcutaneous Dosing. Journal of pharmaceutical sciences 106(6) 1644–1649. DOI:10.1016/j.xphs.2017.02.001 PUBMED:https://pubmed.ncbi.nlm.nih.gov/28189627

  3. Chakraborty, A, et al., & Cheung, W (2005). Population pharmacokinetics of erythropoietin in critically ill subjects. Journal of clinical pharmacology 45(2) 193–202. DOI:10.1177/0091270004269520 PUBMED:https://pubmed.ncbi.nlm.nih.gov/15647412

Revisions


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