.Pharmacolibrary.Drugs.ATC.B.B03XA05 .Pharmacolibrary.Drugs.ATC.B.B03XA05| name: | Roxadustat |
| ATC code: | B03XA05 | route: | oral |
| n-compartments | 2 |
Roxadustat is an orally administered hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI) used primarily for the treatment of anemia associated with chronic kidney disease (CKD). The drug stimulates endogenous erythropoietin production and improves iron metabolism. Roxadustat is approved for clinical use in several countries including China, Japan, and the European Union, but not the United States.
Pharmacokinetics parameters in healthy adult volunteers and CKD patients; population: mixed males and females aged 18-75.
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Shen, ZW, et al., & Lou, Y (2024). Optimizing the dosing regimen of roxadustat in kidney transplant recipients with early post-transplant anemia. Journal of pharmaceutical sciences 113(11) 3344–3353. DOI:10.1016/j.xphs.2024.09.004 PUBMED:https://pubmed.ncbi.nlm.nih.gov/39251067
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