.Pharmacolibrary.Drugs.ATC.B.B05BA10

Information

name:ElectrolyteSolutionsCombinations
ATC code:B05BA10
route:intravenous
n-compartments1

Combinations of electrolyte solutions are used for intravenous fluid replacement in cases of dehydration, electrolyte imbalances, and as carriers for other medications. These solutions typically contain sodium, potassium, chloride, calcium, and sometimes glucose, and are widely approved for use in hospitals and emergency medicine today.

Pharmacokinetics

Pharmacokinetic parameters for intravenous electrolyte combinations are generally not reported for healthy adults as these solutions are primarily used for fluid and electrolyte homeostasis and are not absorbed, distributed, or eliminated via standard pharmacokinetic models. Hence, classic PK parameters such as volume of distribution and clearance are not applicable.

References

  1. Bateman, RM, et al., & Prandi, E (2016). 36th International Symposium on Intensive Care and Emergency Medicine : Brussels, Belgium. 15-18 March 2016. Critical care (London, England) 20(Suppl 2) 94–None. DOI:10.1186/s13054-016-1208-6 PUBMED:https://pubmed.ncbi.nlm.nih.gov/27885969

  2. Levitskaia, TG, et al., & Thrall, KD (2010). Biomaterials for the decorporation of (85)Sr in the rat. Health physics 99(3) 394–400. DOI:10.1097/HP.0b013e3181c4717d PUBMED:https://pubmed.ncbi.nlm.nih.gov/20699703

  3. el-Mougi, M, et al., & Pierce, NF (1996). Efficacy of standard glucose-based and reduced-osmolarity maltodextrin-based oral rehydration solutions: effect of sugar malabsorption. Bulletin of the World Health Organization 74(5) 471–477. PUBMED:https://pubmed.ncbi.nlm.nih.gov/9002327

Revisions


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