.Pharmacolibrary.Drugs.ATC.B.B05CA04 .Pharmacolibrary.Drugs.ATC.B.B05CA04| name: | Sulfamethizole |
| ATC code: | B05CA04 | route: | oral |
| n-compartments | 1 |
Sulfamethizole is a short-acting sulfonamide antibacterial agent that inhibits bacterial folic acid synthesis. It was historically used for the treatment of urinary tract infections but has largely been replaced by newer antibiotics and is not widely used or approved in many countries today.
Pharmacokinetic parameters estimated for a typical healthy adult population based on aggregated literature and drug monographs; limited modern PK studies available.
Zayyad, H, et al., & Paul, M (2017). Revival of old antibiotics: needs, the state of evidence and expectations. International journal of antimicrobial agents 49(5) 536–541. DOI:10.1016/j.ijantimicag.2016.11.021 PUBMED:https://pubmed.ncbi.nlm.nih.gov/28162982