.Pharmacolibrary.Drugs.ATC.B.B05XA04 .Pharmacolibrary.Drugs.ATC.B.B05XA04| name: | AmmoniumChloride |
| ATC code: | B05XA04 | route: | oral |
| n-compartments | 1 |
Ammonium chloride is an inorganic compound used as an expectorant in cough medicines and as a systemic acidifying agent in the treatment of metabolic alkalosis. It has also been used to promote urinary acidification and as a diuretic. Its clinical use is limited today, though it is sometimes applied in laboratory or veterinary settings rather than routinely in human medicine.
Pharmacokinetic parameters estimated for a typical healthy adult after oral administration, as no direct published human PK studies were found.
Liu, R, et al., & Lee, EJ (2011). Effects of sodium bicarbonate and ammonium chloride pre-treatments on PEPT2 (SLC15A2) mediated renal clearance of cephalexin in healthy subjects. Drug metabolism and pharmacokinetics 26(1) 87–93. DOI:10.2133/dmpk.dmpk-10-rg-039 PUBMED:https://pubmed.ncbi.nlm.nih.gov/21084767