.Pharmacolibrary.Drugs.ATC.B.B05XA07 .Pharmacolibrary.Drugs.ATC.B.B05XA07| name: | CalciumChloride |
| ATC code: | B05XA07 | route: | intravenous |
| n-compartments | 1 |
Calcium chloride is an inorganic salt used primarily for the treatment of hypocalcemia, cardiac resuscitation, and as an intravenous electrolyte replenisher. It has emergency applications for severe acute hypocalcemia, hyperkalemia, hypomagnesemia, and as an antidote for calcium channel blocker overdose. It is approved and widely used intravenously in current medical practice.
PK parameters estimated for typical adult (70 kg) healthy subjects based on physicochemical characteristics of calcium and literature on calcium homeostasis. No population-specific published PK models available.
Ansari, JR, et al., & Shafer, SL (2025). Bioequivalence and Pharmacokinetics of Intravenous Calcium during Cesarean Delivery. Anesthesiology 142(1) 121–131. DOI:10.1097/ALN.0000000000005248 PUBMED:https://pubmed.ncbi.nlm.nih.gov/39361822
Bateman, RM, et al., & Prandi, E (2016). 36th International Symposium on Intensive Care and Emergency Medicine : Brussels, Belgium. 15-18 March 2016. Critical care (London, England) 20(Suppl 2) 94–None. DOI:10.1186/s13054-016-1208-6 PUBMED:https://pubmed.ncbi.nlm.nih.gov/27885969
Ansari, JR, et al., & Riley, E (2022). Calcium chloride for the prevention of uterine atony during cesarean delivery: A pilot randomized controlled trial and pharmacokinetic study. Journal of clinical anesthesia 80 110796–None. DOI:10.1016/j.jclinane.2022.110796 PUBMED:https://pubmed.ncbi.nlm.nih.gov/35447502