.Pharmacolibrary.Drugs.ATC.C.C01BA03_1 .Pharmacolibrary.Drugs.ATC.C.C01BA03_1| name: | Disopyramide_1 | |
| ATC code: | C01BA03_1 | route: | intravenous |
| compartments: | 2 | |
| dosage: | 100 | mg |
| volume of distribution: | 0.82 | L |
| clearance: | 3.8 | L/h |
| other parameters in model implementation | ||
Disopyramide is a class IA antiarrhythmic agent used for the management of ventricular and supraventricular arrhythmias. It has anticholinergic and negative inotropic side effects. It is an approved medication in current clinical use.
Pharmacokinetics following intravenous administration in adult healthy subjects.
Kelman, AW, et al., & Bryson, SM (1982). OPT: a package of computer programs for parameter optimisation in clinical pharmacokinetics. British journal of clinical pharmacology 14(2) 247–256. DOI:10.1111/j.1365-2125.1982.tb01969.x PUBMED:https://pubmed.ncbi.nlm.nih.gov/7104175