.Pharmacolibrary.Drugs.ATC.C.C01BB01

Information

Lidocaine is a local anesthetic and antiarrhythmic drug that is primarily used to treat ventricular arrhythmias and to provide local or regional anesthesia. It is approved and widely used in clinical practice today for these indications.

Pharmacokinetics

Pharmacokinetics reported in healthy adult subjects following single intravenous bolus administration.

References

1. Foong, KW, et al., & Loh, PS (2024). Population Pharmacokinetics of Intravenous Lidocaine in Adults: A Systematic Review. Clinical pharmacokinetics 63(5) 623–643. DOI:10.1007/s40262-024-01373-4 PUBMED:https://pubmed.ncbi.nlm.nih.gov/38703307

2. Heath, C, et al., & Sommerfield, D (2023). Perioperative intravenous lidocaine use in children. Paediatric anaesthesia 33(5) 336–346. DOI:10.1111/pan.14608 PUBMED:https://pubmed.ncbi.nlm.nih.gov/36424875

3. Crouch, CE, et al., & Fernandez-Bustamante, A (2023). Lidocaine Intraoperative Infusion Pharmacokinetics during Partial Hepatectomy for Living Liver Donation. Anesthesiology 138(1) 71–81. DOI:10.1097/ALN.0000000000004422 PUBMED:https://pubmed.ncbi.nlm.nih.gov/36512707

Revisions

• 06/2025 initial generated model