name: | Arbutamine | |
ATC code: | C01CA22 | route: | intravenous |
compartments: | 2 | |
dosage: | 3 | mg |
volume of distribution: | 0.3 | L |
clearance: | 1500 | mL/min |
other parameters in model implementation |
Arbutamine is a synthetic catecholamine and sympathomimetic agent that acts as a beta-adrenergic agonist. It was developed primarily for use as a pharmacologic agent in cardiac stress testing (myocardial perfusion imaging) in patients unable to exercise adequately. Arbutamine is not widely used today and has been discontinued in many markets; it is not approved for current clinical use.
No published pharmacokinetic data could be found for arbutamine in humans. Neither population nor single-dose PK studies in adults are referenced in the literature. The parameters below are estimated based on its class and general properties of similar beta-agonists (e.g., dobutamine).