name: | Regadenoson |
ATC code: | C01EB21 | route: | intravenous |
n-compartments | 3 |
Regadenoson is a selective adenosine A2A receptor agonist used as a pharmacologic stress agent in myocardial perfusion imaging (MPI) for the diagnosis of coronary artery disease. It is approved and widely used in clinical practice as a cardiac stress agent.
Pharmacokinetics in healthy adult subjects and patients with coronary artery disease; parameters primarily reported for intravenous bolus administration.
Gordi, T, et al., & Lieu, H (2006). A population pharmacokinetic/pharmacodynamic analysis of regadenoson, an adenosine A2A-receptor agonist, in healthy male volunteers. Clinical pharmacokinetics 45(12) 1201–1212. DOI:10.2165/00003088-200645120-00005 PUBMED:https://pubmed.ncbi.nlm.nih.gov/17112296
Gordi, T, et al., & Lieu, H (2007). Regadenoson pharmacokinetics and tolerability in subjects with impaired renal function. Journal of clinical pharmacology 47(7) 825–833. DOI:10.1177/0091270007301620 PUBMED:https://pubmed.ncbi.nlm.nih.gov/17585115