.Pharmacolibrary.Drugs.ATC.C.C02AC02 .Pharmacolibrary.Drugs.ATC.C.C02AC02| name: | Guanfacine | |
| ATC code: | C02AC02 | route: | oral |
| compartments: | 1 | |
| dosage: | 3 | mg |
| volume of distribution: | 6.3 | L |
| clearance: | 1.0 | L/h/kg |
| other parameters in model implementation | ||
Guanfacine is an oral antihypertensive agent that acts as a selective alpha-2A adrenergic receptor agonist. It is used in the management of hypertension and, more recently, for the treatment of attention deficit hyperactivity disorder (ADHD) in children and adolescents. Guanfacine is approved and is still in clinical use.
Pharmacokinetic parameters reported for healthy adult volunteers following oral administration.
De Hondt, L, et al., & Tommelein, E (2024). Quantification of ADHD medication in biological fluids of pregnant and breastfeeding women with liquid chromatography: a comprehensive review. Frontiers in public health 12 1437328–None. DOI:10.3389/fpubh.2024.1437328 PUBMED:https://pubmed.ncbi.nlm.nih.gov/39171321