.Pharmacolibrary.Drugs.ATC.C.C02CA01

Information

name:Prazosin
ATC code:C02CA01
route:oral
n-compartments2

Prazosin is an alpha-1 adrenergic receptor antagonist primarily used for the treatment of hypertension and symptoms of benign prostatic hyperplasia. It is also used off-label in the management of post-traumatic stress disorder (PTSD)-associated nightmares in adults. Prazosin is an approved and commonly used medication today.

Pharmacokinetics

Pharmacokinetic parameters reported in healthy adult male subjects after oral administration.

References

  1. Kwon, YH, et al., & Chun, IK (2007). Pharmacokinetics of doxazosin gastrointestinal therapeutic system after multiple administration in Korean healthy volunteers. Drug development and industrial pharmacy 33(8) 824–829. DOI:10.1080/03639040601012999 PUBMED:https://pubmed.ncbi.nlm.nih.gov/17729099

  2. Liu, M, et al., & Liu, H (2012). Pharmacokinetics of terazosin enantiomers in healthy Chinese male subjects. Chirality 24(12) 1047–1050. DOI:10.1002/chir.22095 PUBMED:https://pubmed.ncbi.nlm.nih.gov/22887707

  3. Yan, M, et al., & Zhu, YG (2010). Determination of metoclopramide in human plasma by LC-ESI-MS and its application to bioequivalance studies. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 878(11-12) 883–887. DOI:10.1016/j.jchromb.2010.02.006 PUBMED:https://pubmed.ncbi.nlm.nih.gov/20189472

Revisions


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