.Pharmacolibrary.Drugs.ATC.C.C02KB01 .Pharmacolibrary.Drugs.ATC.C.C02KB01| name: | Metirosine |
| ATC code: | C02KB01 | route: | oral |
| n-compartments | 1 |
Metirosine (alpha-methyltyrosine) is a competitive inhibitor of tyrosine hydroxylase, the rate-limiting enzyme in catecholamine biosynthesis. It is used primarily to manage symptoms of pheochromocytoma, a catecholamine-secreting tumor, especially preoperatively or in patients where surgery is contraindicated. Its use today is rare and limited to specific indications.
Pharmacokinetic estimates based on available secondary literature and drug labeling for healthy adult individuals; no detailed compartmental modeling PK study found.