.Pharmacolibrary.Drugs.ATC.C.C03CA01 .Pharmacolibrary.Drugs.ATC.C.C03CA01| name: | Furosemide |
| ATC code: | C03CA01 | route: | oral |
| n-compartments | 2 |
Furosemide is a potent loop diuretic used primarily to treat edema associated with congestive heart failure, liver cirrhosis, and renal disease, as well as hypertension. It is approved for use and remains a mainstay in acute and chronic treatment of fluid overload.
Pharmacokinetic parameters reported for healthy adult subjects following a single oral dose.
Van Wart, SA, et al., & Mager, DE (2014). Population-based meta-analysis of furosemide pharmacokinetics. Biopharmaceutics & drug disposition 35(2) 119–133. DOI:10.1002/bdd.1874 PUBMED:https://pubmed.ncbi.nlm.nih.gov/24151207
Pelligand, L, et al., & Jacobs, M (2020). Population Pharmacokinetics and Pharmacodynamics Modeling of Torasemide and Furosemide After Oral Repeated Administration in Healthy Dogs. Frontiers in veterinary science 7 151–None. DOI:10.3389/fvets.2020.00151 PUBMED:https://pubmed.ncbi.nlm.nih.gov/32411731
Kodati, D, & Yellu, N (2017). Population pharmacokinetic modeling of furosemide in patients with hypertension and fluid overload conditions. Pharmacological reports : PR 69(3) 492–496. DOI:10.1016/j.pharep.2017.01.006 PUBMED:https://pubmed.ncbi.nlm.nih.gov/28340405