.Pharmacolibrary.Drugs.ATC.C.C05AD01 .Pharmacolibrary.Drugs.ATC.C.C05AD01| name: | Lidocaine | |
| ATC code: | C05AD01 | route: | intravenous |
| compartments: | 2 | |
| dosage: | 100 | mg |
| volume of distribution: | 0.7 | L |
| clearance: | 10 | ml/min/kg |
| other parameters in model implementation | ||
Lidocaine is a local anesthetic and antiarrhythmic drug of the amide type, widely used for local anesthesia, regional anesthesia, and the treatment of ventricular arrhythmias. Lidocaine is FDA-approved and continues to be used extensively in medical practice.
Pharmacokinetic parameters reported in healthy adult individuals, both males and females, after intravenous administration.
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Heath, C, et al., & Sommerfield, D (2023). Perioperative intravenous lidocaine use in children. Paediatric anaesthesia 33(5) 336–346. DOI:10.1111/pan.14608 PUBMED:https://pubmed.ncbi.nlm.nih.gov/36424875
Crouch, CE, et al., & Fernandez-Bustamante, A (2023). Lidocaine Intraoperative Infusion Pharmacokinetics during Partial Hepatectomy for Living Liver Donation. Anesthesiology 138(1) 71–81. DOI:10.1097/ALN.0000000000004422 PUBMED:https://pubmed.ncbi.nlm.nih.gov/36512707