name: | Propranolol_1 |
ATC code: | C07AA05_1 | route: | intravenous |
n-compartments | 2 |
Propranolol is a non-selective beta-adrenergic receptor blocker used for the management of hypertension, angina pectoris, arrhythmias, myocardial infarction, and for the prevention of migraine headaches. It is one of the first beta-blockers developed and is widely approved for clinical use today.
Pharmacokinetic parameters following intravenous administration in healthy adults.
Cheymol, G, et al., & Dry, J (1987). Comparative pharmacokinetics of intravenous propranolol in obese and normal volunteers. Journal of clinical pharmacology 27(11) 874–879. DOI:10.1002/j.1552-4604.1987.tb05582.x PUBMED:https://pubmed.ncbi.nlm.nih.gov/3429695
Venter, CP, et al., & Strydom, WJ (1985). Comparative pharmacokinetics of intravenous propranolol in black and white volunteers. Journal of cardiovascular pharmacology 7(2) 409–410. DOI:10.1097/00005344-198503000-00029 PUBMED:https://pubmed.ncbi.nlm.nih.gov/2581098
Weiss, YA, et al., & Alexandre, JM (1976). Comparison of the pharmacokinetics of intravenous dl-propranolol in borderline and permanent hypertension. European journal of clinical pharmacology 10(6) 387–393. DOI:10.1007/BF00563074 PUBMED:https://pubmed.ncbi.nlm.nih.gov/1001353