.Pharmacolibrary.Drugs.ATC.C.C07AA06

Information

Timolol is a non-selective beta-adrenergic antagonist (beta-blocker) used primarily to treat hypertension, angina pectoris, and in ophthalmic form for increased intraocular pressure in glaucoma. It is approved for clinical use and available in systemic and ophthalmic formulations.

Pharmacokinetics

Pharmacokinetic parameters reported in healthy adult volunteers after a single oral dose.

References

1. Olsen, GM, et al., & Drolet, BA (2020). Evaluating the Safety of Oral Propranolol Therapy in Patients With PHACE Syndrome. JAMA dermatology 156(2) 186–190. DOI:10.1001/jamadermatol.2019.3839 PUBMED:https://pubmed.ncbi.nlm.nih.gov/31825455

2. Salminen, L, et al., & Iisalo, E (1989). Prevalence of debrisoquine oxidation phenotypes in glaucoma patients. International ophthalmology 13(1-2) 91–93. DOI:10.1007/BF02028645 PUBMED:https://pubmed.ncbi.nlm.nih.gov/2787298

Revisions

• 06/2025 initial generated model