.Pharmacolibrary.Drugs.ATC.C.C07AG01_1 .Pharmacolibrary.Drugs.ATC.C.C07AG01_1| name: | Labetalol_1 | |
| ATC code: | C07AG01_1 | route: | orally |
| compartments: | 1 | |
| dosage: | 200 | mg |
| volume of distribution: | 6.3 | L |
| clearance: | 370 | ml/min |
| other parameters in model implementation | ||
Labetalol is a combined alpha- and beta-adrenergic receptor antagonist used primarily for the treatment of hypertension, including hypertensive emergencies and chronic hypertension. It is approved for clinical use and is widely prescribed today.
Pharmacokinetic parameters from healthy adult subjects after single oral administration.
Rasmussen, BB, et al., & Senderovitz, T (2005). Pharmacokinetic interaction studies of atosiban with labetalol or betamethasone in healthy female volunteers. BJOG : an international journal of obstetrics and gynaecology 112(11) 1492–1499. DOI:10.1111/j.1471-0528.2005.00735.x PUBMED:https://pubmed.ncbi.nlm.nih.gov/16225568