.Pharmacolibrary.Drugs.ATC.C.C08CA11 .Pharmacolibrary.Drugs.ATC.C.C08CA11| name: | Manidipine | |
| ATC code: | C08CA11 | route: | oral |
| compartments: | 2 | |
| dosage: | 20 | mg |
| volume of distribution: | 80 | L |
| clearance: | 60 | L/h |
| other parameters in model implementation | ||
Manidipine is a dihydropyridine calcium channel blocker used for the treatment of hypertension. It lowers blood pressure by inhibiting the influx of calcium ions through L-type calcium channels in vascular smooth muscle, resulting in vasodilation. It is an orally active antihypertensive agent approved in several countries.
Pharmacokinetics reported in healthy adult male volunteers after single oral 20 mg dose.