.Pharmacolibrary.Drugs.ATC.C.C08CX01

Information

name:	Mibefradil
ATC code:	C08CX01
route:	oral
compartments:	2
dosage:	100	mg
volume of distribution:	35	L
clearance:	25	L/h
other parameters in model implementation

Mibefradil is a calcium channel blocker formerly used as an antihypertensive and antianginal agent. It was primarily used for the treatment of hypertension and chronic stable angina pectoris. Due to serious drug interactions, mibefradil was withdrawn from the market in 1998 and is not used in clinical practice today.

Pharmacokinetics

Pharmacokinetic parameters from studies in healthy adult volunteers after oral administration.

References

Welker, HA, & Banken, L (1998). Mibefradil pharmacokinetic and pharmacodynamic population analysis. International journal of clinical pharmacology research 18(2) 63–71. PUBMED:https://pubmed.ncbi.nlm.nih.gov/9675623

Revisions

06/2025 Tomas Kulhanek, generated model from data extracted from PUBMED, DrugBank and LLM(GPT4.1)

Generated at 2025-08-10T18:21:06Z by OpenModelicaOpenModelica 1.25.1 using GenerateDoc.mos