.Pharmacolibrary.Drugs.ATC.C.C09AA09

Information

name:Fosinopril
ATC code:C09AA09
route:oral
n-compartments1

Fosinopril is an angiotensin-converting enzyme (ACE) inhibitor indicated for the treatment of hypertension and heart failure. It is a prodrug that is converted to its active form, fosinoprilat, in the liver. Fosinopril is approved and widely used in current clinical practice.

Pharmacokinetics

Pharmacokinetic parameters reported for healthy adult volunteers following a single oral dose.

References

  1. Ding, PY, et al., & Liao, WC (1999). Fosinopril: pharmacokinetics and pharmacodynamics in Chinese subjects. Journal of clinical pharmacology 39(2) 155–160. DOI:10.1177/00912709922007705 PUBMED:https://pubmed.ncbi.nlm.nih.gov/11563407

  2. Ding, PY, et al., & Liao, W (2000). Does Chinese ethnicity affect the pharmacokinetics and pharmacodynamics of angiotensin-converting enzyme inhibitors?. Journal of human hypertension 14(3) 163–170. DOI:10.1038/sj.jhh.1000856 PUBMED:https://pubmed.ncbi.nlm.nih.gov/10694829

  3. Hu, OY, et al., & Chu, KM (1997). Pharmacokinetics of fosinoprilat in Chinese and whites after intravenous administration. Journal of clinical pharmacology 37(9) 834–840. DOI:10.1002/j.1552-4604.1997.tb05632.x PUBMED:https://pubmed.ncbi.nlm.nih.gov/9549638

Revisions

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