.Pharmacolibrary.Drugs.ATC.C.C09BA01 .Pharmacolibrary.Drugs.ATC.C.C09BA01| name: | CaptoprilAndDiuretics |
| ATC code: | C09BA01 | route: | oral |
| n-compartments | 1 |
Captopril is an angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and some types of heart failure; when combined with diuretics, the mixture enhances blood pressure reduction by promoting excretion of water and salt. This fixed dose combination is approved and commonly used in clinical practice.
Pharmacokinetic parameters for captopril and diuretic fixed-combination product in healthy adult volunteers (values mostly reflect captopril component, as diuretics vary depending on formulation).
Langtry, HD, & Markham, A (1997). Lisinopril. A review of its pharmacology and clinical efficacy in elderly patients. Drugs & aging 10(2) 131–166. DOI:10.2165/00002512-199710020-00006 PUBMED:https://pubmed.ncbi.nlm.nih.gov/9061270