.Pharmacolibrary.Drugs.ATC.C.C09BX05 .Pharmacolibrary.Drugs.ATC.C.C09BX05| name: | RamiprilAndBisoprolol | |
| ATC code: | C09BX05 | route: | oral |
| compartments: | 1 | |
| dosage: | 5 | mg |
| volume of distribution: | 96 | L |
| clearance: | 15 | L/h |
| other parameters in model implementation | ||
Ramipril is an angiotensin-converting enzyme (ACE) inhibitor used primarily for the treatment of hypertension and congestive heart failure, while bisoprolol is a selective beta-1 adrenergic receptor blocker used to manage hypertension, angina, and heart failure. The combination is used for optimized management of hypertension, particularly in patients with comorbid cardiovascular conditions. The fixed-dose combination with ATC C09BX05 is approved and available in several countries.
Pharmacokinetic parameters for the fixed-dose combination of ramipril and bisoprolol (ATC C09BX05) have not been reported in a dedicated published pharmacokinetic population model in the literature. The following parameters are provided as estimates based on known monotherapy pharmacokinetics of ramipril and bisoprolol in healthy adults.