.Pharmacolibrary.Drugs.ATC.C.C09DX07 .Pharmacolibrary.Drugs.ATC.C.C09DX07| name: | IrbesartanAmlodipineAndHydrochlorothiazide | |
| ATC code: | C09DX07 | route: | oral |
| compartments: | 1 | |
| dosage: | 300 | mg |
| volume of distribution: | 50 | L |
| clearance: | 1.5 | L/h |
| other parameters in model implementation | ||
Fixed combination tablet of irbesartan (an angiotensin II receptor blocker), amlodipine (a calcium channel blocker), and hydrochlorothiazide (a thiazide diuretic) used for the treatment of essential hypertension in adults; currently approved and used in clinical practice when multi-drug therapy is indicated.
Estimated composite pharmacokinetic parameters for healthy adult subjects, based on published data of individual components. No direct study of triple-combination PK model found.