.Pharmacolibrary.Drugs.ATC.C.C10AA04_1 .Pharmacolibrary.Drugs.ATC.C.C10AA04_1| name: | Fluvastatin_1 |
| ATC code: | C10AA04_1 | route: | oral |
| n-compartments | 2 |
Fluvastatin is an orally administered lipid-lowering agent that belongs to the statin class of drugs. It is primarily used to reduce levels of cholesterol and triglycerides in the blood and is approved for the treatment of hypercholesterolemia and mixed dyslipidemia to prevent cardiovascular disease.
Pharmacokinetic model parameters for oral administration of 40 mg fluvastatin capsule in Japanese healthy adult subjects.
Xu, HR, et al., & Zhu, JR (2012). The difference in pharmacokinetics and pharmacodynamics between extended-release fluvastatin and immediate-release fluvastatin in healthy Chinese subjects. Journal of biomedicine & biotechnology 2012 386230–None. DOI:10.1155/2012/386230 PUBMED:https://pubmed.ncbi.nlm.nih.gov/22811596
Kirchheiner, J, & Brockmöller, J (2005). Clinical consequences of cytochrome P450 2C9 polymorphisms. Clinical pharmacology and therapeutics 77(1) 1–16. DOI:10.1016/j.clpt.2004.08.009 PUBMED:https://pubmed.ncbi.nlm.nih.gov/15637526
Pincus, KJ, & Hynicka, LM (2013). Prophylaxis of thromboembolic events in patients with nephrotic syndrome. The Annals of pharmacotherapy 47(5) 725–734. DOI:10.1345/aph.1R530 PUBMED:https://pubmed.ncbi.nlm.nih.gov/23613095